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Literature summary for 1.14.16.4 extracted from

  • Yohrling, I.G.; Jiang, G.C.; DeJohn, M.M.; Robertson, D.J.; Vrana, K.E.; Cha, J.H.
    Inhibition of tryptophan hydroxylase activity and decreased 5-HT1A receptor binding in a mouse model of Huntington's disease (2002), J. Neurochem., 82, 1416-1423.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Mus musculus
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transgenic mice containing exon 1 of the human huntigton gene
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Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
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enzyme activity decreases in 4-, 8-, and 12-week-old mice expressing exon 1 of human huntingtin gene by 62, 61 and 86% respectively compared to control animals Mus musculus