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Literature summary for 1.14.16.1 extracted from
- Kinetic mechanism of phenylalanine hydroxylase: intrinsic binding and rate constants from single-turnover experiments (2013), Biochemistry, 52, 1062-1073.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| the truncated enzyme PheHDELTA117 is expressed in Escherichia coli BL21(DE3) cells | Rattus norvegicus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-phenylalanine + tetrahydrobiopterin + O2 | Rattus norvegicus | - |
L-tyrosine + 4a-hydroxytetrahydrobiopterin | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-phenylalanine + 6-methyltetrahydropterin + O2 | low activity with 6-methyltetrahydropterin | Rattus norvegicus | L-tyrosine + 4a-hydroxy-6-methyltetrahydropterin | - |
? | |
| L-phenylalanine + tetrahydrobiopterin + O2 | - |
Rattus norvegicus | L-tyrosine + 4a-hydroxytetrahydrobiopterin | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| PheH | - |
Rattus norvegicus |
| phenylalanine hydroxylase | - |
Rattus norvegicus |
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Release 2023.1 (January 2023)
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