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Literature summary for 1.14.16.1 extracted from

  • Bloom, L.M.; Benkovic, S.J.; Gaffney, B.J.
    Characterization of phenylalanine hydroxylase (1986), Biochemistry, 25, 4204-4210.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
epinephrine
-
Rattus norvegicus

Metals/Ions

Metals/Ions Comment Organism Structure
Iron iron can be removed by treatment with o-phenanthroline, reconstitution of apoenzyme with iron restores 90% of the initial activity Rattus norvegicus
Iron iron-protein Rattus norvegicus
Iron electron paramagnetic resonance spectrum Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-phenylalanine + tetrahydrobiopterin + O2
-
Rattus norvegicus L-tyrosine + dihydrobiopterin + H2O
-
?

Cofactor

Cofactor Comment Organism Structure
tetrahydrobiopterin
-
Rattus norvegicus