Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
corticosterone + reduced adrenal ferredoxin + O2 | Homo sapiens | - |
18-hydroxycorticosterone + oxidized adrenal ferredoxin + H2O | - |
? | |
additional information | Homo sapiens | reduced enzyme activity occurs in hyponatremia and hyperkalemia due to an isolated aldosterone biosynthesis defect, the phenotype can be rescued by a fludrocortisone replacement therapy, overview | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
corticosterone + reduced adrenal ferredoxin + O2 | - |
Homo sapiens | 18-hydroxycorticosterone + oxidized adrenal ferredoxin + H2O | - |
? | |
additional information | reduced enzyme activity occurs in hyponatremia and hyperkalemia due to an isolated aldosterone biosynthesis defect, the phenotype can be rescued by a fludrocortisone replacement therapy, overview | Homo sapiens | ? | - |
? |