Literature summary for 1.14.15.3 extracted from

Kawashima, H.; Naganuma, T.; Kusunose, E.; Kono, T.; Yasumoto, R.; Sugimura, K.; Kishimoto, T.
Human fatty acid omega-hydroxylase, CYP4A11: determination of complete genomic sequence and characterization of purified recombinant protein (2000), Arch. Biochem. Biophys., 378, 333-339.

Search for more literature for 1.14.15.3

Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Escherichia coli, human gene CYP4A11	Homo sapiens

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
0.057	-	laurate	gene CYP4A11	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
arachidonic acid + NAD(P)H + H+ + O2	-	Homo sapiens	20-hydroxyicosa-5,8,11,14-tetraenoic acid + NAD(P)+ + H2O	-	?
fatty acid + NAD(P)H + H+ + O2	medium-chain fatty acids	Homo sapiens	omega-hydroxy fatty acid + NAD(P)+ + H2O	-	?
lauric acid + NAD(P)H + H+ + O2	-	Homo sapiens	12-hydroxydodecanoic acid + NAD(P)+ + H2O	-	?
palmitic acid + NAD(P)H + H+ + O2	-	Homo sapiens	16-hydroxyhexadecanoic acid + NAD(P)+ + H2O	-	?

Turnover Number [1/s]

Turnover Number Minimum [1/s]	Turnover Number Maximum [1/s]	Substrate	Comment	Organism	Structure
0.013	-	palmitate	omega-hydroxylation	Homo sapiens
0.245	-	laurate	omega-hydroxylation	Homo sapiens

Cofactor

Cofactor	Comment	Organism	Structure
NADPH	-	Homo sapiens

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Release 2023.1 (January 2023)