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Literature summary for 1.14.15.16 extracted from

  • Hoebaus, J.; Fetahu, I.S.h.; Khorchide, M.; Manhardt, T.; Kallay, E.
    Epigenetic regulation of the 1,25-dihydroxyvitamin D3 24-hydroxylase (CYP24A1) in colon cancer cells (2013), J. Steroid Biochem. Mol. Biol., 136, 296-299.
    View publication on PubMedView publication on EuropePMC
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Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
-

Source Tissue

Source Tissue Comment Organism Textmining
Caco-2/AQ cell
-
 Homo sapiens
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COGA-13 cell
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 Homo sapiens
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COGA-1A cell
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 Homo sapiens
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colonic cancer cell
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 Homo sapiens
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HT-29 cell
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 Homo sapiens
-

Synonyms

Synonyms Comment Organism
1,25-dihydroxyvitamin D3 24-hydroxylase
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 Homo sapiens
CYP24A1
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 Homo sapiens

Expression

Organism Comment Expression
Homo sapiens methyltransferase inhibitor 5-aza-2'-deoxycytidine treatment results in an over 50fold induction of CYP24A1 mRNA expression in Coga1A and HT-29 cells. In colon cancer cells, CYP24A1 gene expression is inducible by methyltransferase and some histone deacetylase inhibitors in a cell line-dependent manner up