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Literature summary for 1.14.15.15 extracted from

  • Sato, R.; Atsuta, Y.; Imai, Y.; Taniguchi, S.; Okuda, K.
    Hepatic mitochondrial cytochrome P-450: isolation and functional characterization (1977), Proc. Natl. Acad. Sci. USA, 74, 5477-5481.
    View publication on PubMedView publication on EuropePMC
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Inhibitors

Inhibitors Comment Organism Structure
CO 62% inhibition at 25%O2/75%CO Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrial membrane
-
 Rattus norvegicus 31966
-

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
partial Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-

Storage Stability

Storage Stability Organism
-70°C, no loss of activity for 5 months Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5beta-cholestane-3alpha,7alpha,12alpha-triol + reduced adrenodoxin + O2
-
 Rattus norvegicus 5beta-cholestane-3alpha,7alpha,12alpha,27-tetrol + oxidized adrenodoxin + H2O
-
 ?

Cofactor

Cofactor Comment Organism Structure
cytochrome P450 inner mitochondrial membrane houses a species of cytochrome-P450 functional in 5beta-cholestane-3alpha,7alpha,12alpha-triol 26-hydroxylation Rattus norvegicus
NADPH
-
 Rattus norvegicus