Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Iron | heme iron | Pseudomonas putida |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
(+)-camphor + O2 + reduced putidaredoxin | Pseudomonas putida | - |
(+)-exo-5-hydroxycamphor + oxidized putidaredoxin + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Pseudomonas putida | P00183 | - |
- |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
(+)-camphor + reduced putidaredoxin + O2 = (+)-exo-5-hydroxycamphor + oxidized putidaredoxin + H2O | the active site structure changes due to putidaredoxin-enzyme interaction involving salt bridge and hydrogen bonding network between Arg112, His355, Leu356, and the heme ligand Cys357 | Pseudomonas putida |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(+)-camphor + O2 + reduced putidaredoxin | - |
Pseudomonas putida | (+)-exo-5-hydroxycamphor + oxidized putidaredoxin + H2O | - |
? | |
(+)-camphor + O2 + reduced putidaredoxin | analysis of protein-protein interactions between enzyme and cofactor, overview | Pseudomonas putida | (+)-exo-5-hydroxycamphor + oxidized putidaredoxin + H2O | - |
? |
Subunits | Comment | Organism |
---|---|---|
More | structural changes upon complex formation between enzyme and cofactor cause an increase in beta-sheets and alpha-helix content, a decrease in population of random coil/3 10-helix structure, a redistribution of turn structures within the interacting proteins and changes in the protonation states or hydrogen-bondonh of amino acid carboxylic side chains | Pseudomonas putida |
Synonyms | Comment | Organism |
---|---|---|
CYP101 | - |
Pseudomonas putida |
cytochrome p450cam | - |
Pseudomonas putida |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
putidaredoxin | analysis of protein-protein interactions between enzyme and cofactor, structural changes upon complex formation, overview | Pseudomonas putida |