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Literature summary for 1.14.14.21 extracted from

  • Park, H.S.; Kayser, K.J.; Kwak, J.H.; Kilbane, J.J.
    Heterologous gene expression in Thermus thermophilus: beta-galactosidase, dibenzothiophene monooxygenase, PNB carboxy esterase, 2-aminobiphenyl-2,3-diol dioxygenase, and chloramphenicol acetyl transferase (2004), J. Ind. Microbiol. Biotechnol., 31, 189-197.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
gene dszC, functional recombinant enzyme expression in Thermus thermophilus strain HB27 Rhodococcus erythropolis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
dibenzothiophene-5,5-dioxide + 2 FMNH2 + O2 Rhodococcus erythropolis
-
2'-hydroxybiphenyl-2-sulfinate + 2 FMN + H2O
-
?
dibenzothiophene-5,5-dioxide + 2 FMNH2 + O2 Rhodococcus erythropolis IGTS8 / ATCC 53968
-
2'-hydroxybiphenyl-2-sulfinate + 2 FMN + H2O
-
?

Organism

Organism UniProt Comment Textmining
Rhodococcus erythropolis A0SWL2 gene dszC
-
Rhodococcus erythropolis IGTS8 / ATCC 53968 A0SWL2 gene dszC
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
dibenzothiophene-5,5-dioxide + 2 FMNH2 + O2
-
Rhodococcus erythropolis 2'-hydroxybiphenyl-2-sulfinate + 2 FMN + H2O
-
?
dibenzothiophene-5,5-dioxide + 2 FMNH2 + O2
-
Rhodococcus erythropolis IGTS8 / ATCC 53968 2'-hydroxybiphenyl-2-sulfinate + 2 FMN + H2O
-
?

Synonyms

Synonyms Comment Organism
cofactor-requiring dibenzothiophene monooxygenase
-
Rhodococcus erythropolis
dibenzothiophene monooxygenase
-
Rhodococcus erythropolis
dszC
-
Rhodococcus erythropolis

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
assay at Rhodococcus erythropolis

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7
-
assay at Rhodococcus erythropolis

Cofactor

Cofactor Comment Organism Structure
FMNH2
-
Rhodococcus erythropolis
additional information the enzyme requires NADH, FMNH2, oxygen, and the aid of NADH-FMN oxidoreductase to catalyze the conversion of dibenzothiophene Rhodococcus erythropolis
NADH
-
Rhodococcus erythropolis