Cloned (Comment) | Organism |
---|---|
gene P450c17-I, DNA and amino acid sequence determination and analysis, phylogenetic analysis, semiquantitative RT-PCR enzyme expression analysis | Verasper moseri |
gene P450c17-II, DNA and amino acid sequence determination and analysis, phylogenetic analysis, semiquantitative RT-PCR enzyme expression analysis | Verasper moseri |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Verasper moseri | B3VLB1 | P450c17-I; male fish from an aquatic farm in Yantai City, Shandong, China, gene P450c17-I | - |
Verasper moseri | B6UPD2 | P450c17-II; male fish from an aquatic farm in Yantai City, Shandong, China, gene P450c17-II | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Verasper moseri | - |
head kidney | high level of P450c17-II expression | Verasper moseri | - |
kidney | - |
Verasper moseri | - |
additional information | semiquantitative RT-PCR enzyme tissue expression analysis, P450c17-I mRNA expression during the testicular cycle, overview | Verasper moseri | - |
additional information | semiquantitative RT-PCR enzyme tissue expression analysis, P450c17-II mRNA expression during the testicular cycle, overview | Verasper moseri | - |
ovary | - |
Verasper moseri | - |
testis | - |
Verasper moseri | - |
testis | high level of P450c17-I | Verasper moseri | - |
Synonyms | Comment | Organism |
---|---|---|
P450c17 | - |
Verasper moseri |
General Information | Comment | Organism |
---|---|---|
physiological function | P450c17, a key steroidogenic enzyme, plays important roles in the production of sex steroid and cortisol. In teleost, there are two types of P450c17, P450c17-I possessing 17alpha-hydroxylase and 17,20-lyase activities, and P450c17-II only possessing 17alpha-hydroxylase activity. Only P450c17-II is involved in the production of cortisol in barfin flounder | Verasper moseri |
physiological function | P450c17, a key steroidogenic enzyme, plays important roles in the production of sex steroid and cortisol. In teleost, there are two types of P450c17, P450c17-I possessing 17alpha-hydroxylase and 17,20-lyase activities, and P450c17-II only possessing 17alpha-hydroxylase activity. P450c17-I is not involved in the production of cortisol in barfin flounder | Verasper moseri |