Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli BL21 cells | Mus musculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
nucleus | - |
Mus musculus | 5634 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
28000 | - |
x * 28000, isoform HO-1, SDS-PAGE | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Mus musculus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
LNCaP cell | - |
Mus musculus | - |
MEF cell | - |
Mus musculus | - |
Subunits | Comment | Organism |
---|---|---|
? | x * 28000, isoform HO-1, SDS-PAGE | Mus musculus |
Synonyms | Comment | Organism |
---|---|---|
heme oxygenase-1 | - |
Mus musculus |
HO-1 | - |
Mus musculus |
Organism | Comment | Expression |
---|---|---|
Mus musculus | isoform HO-1 is induced by oxidative stress and cancer | up |
General Information | Comment | Organism |
---|---|---|
metabolism | isoform HO-1 modulates the function of transcriptional factor Nuclear factor erythroid 2-related factor 2 (Nrf2). In oxidative stress, nuclear isoform HO-1 interacts with Nrf2 and stabilizes it from glycogen synthase kinase 3beta-mediated phosphorylation coupled with ubiquitin-proteasomal degradation, thereby prolonging its accumulation in the nucleus | Mus musculus |