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Literature summary for 1.14.14.18 extracted from

  • Kim, B.C.; Jeon, W.K.; Hong, H.Y.; Jeon, K.B.; Hahn, J.H.; Kim, Y.M.; Numazawa, S.; Yosida, T.; Park, E.H.; Lim, C.J.
    The anti-inflammatory activity of Phellinus linteus (Berk. & M.A. Curt.) is mediated through the PKCdelta/Nrf2/ARE signaling to up-regulation of heme oxygenase-1 (2007), J. Ethnopharmacol., 113, 240-247.
    View publication on PubMed
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Activating Compound

Activating Compound Comment Organism Structure
additional information the PKCdelta/Nrf2/ARE signaling up-regulates heme oxygenase-1 Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
heme + AH2 + O2 Mus musculus
-
 biliverdin + Fe2+ + CO + A + H2O
-
 ?
additional information Mus musculus the anti-inflammatory activity of Phellinus linteus is mediated through the PKCdelta/Nrf2/ARE signaling to up-regulation of heme oxygenase-1 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus P14901
-
-

Source Tissue

Source Tissue Comment Organism Textmining
macrophage
-
 Mus musculus
-
RAW-264.7 cell
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
heme + AH2 + O2
-
 Mus musculus biliverdin + Fe2+ + CO + A + H2O
-
 ?
additional information the anti-inflammatory activity of Phellinus linteus is mediated through the PKCdelta/Nrf2/ARE signaling to up-regulation of heme oxygenase-1 Mus musculus ?
-
 ?

Synonyms

Synonyms Comment Organism
heme oxygenase-1
-
 Mus musculus
HO-1
-
 Mus musculus