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Literature summary for 1.14.14.18 extracted from
- Cadmium-responsive element of the human heme oxygenase-1 gene mediates heat shock factor 1-dependent transcriptional activation (2007), J. Biol. Chem., 282, 8715-8723.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| heme + AH2 + O2 | Homo sapiens | heat shock factor 1, HSF1, is directly involved in the transcriptional regulation of ho-1 mediated by the enzyme's cadmium-responsive element, mechanism, overview | biliverdin + Fe2+ + CO + A + H2O | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
gene ho-1 | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| HeLa-S3 cell | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| heme + AH2 + O2 | - |
Homo sapiens | biliverdin + Fe2+ + CO + A + H2O | - |
? | |
| heme + AH2 + O2 | heat shock factor 1, HSF1, is directly involved in the transcriptional regulation of ho-1 mediated by the enzyme's cadmium-responsive element, mechanism, overview | Homo sapiens | biliverdin + Fe2+ + CO + A + H2O | - |
? | |
| additional information | ho-1 forms complexes with proteins from heavy metal-treated HeLa cells | Homo sapiens | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| heme oxygenase-1 | - |
Homo sapiens |
| HO-1 | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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