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Literature summary for 1.14.13.81 extracted from
- The chlorophyll biosynthetic enzyme Mg-protoporphyrin IX monomethyl ester (oxidative) cyclase. Characterization and partial purification from Chlamydomonas reinhardtii and Synechocystis sp. PCC 6803 (1996), Plant Physiol., 112, 105-114.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| ascorbate | prevents degradation of tetrapyrroles by reactive oxygen species | Chlamydomonas reinhardtii |  |
| ascorbate | prevents degradation of tetrapyrroles by reactive oxygen species | Synechocystis sp. | |
| catalase | prevents degradation of tetrapyrroles by reactive oxygen species | Chlamydomonas reinhardtii | |
| catalase | prevents degradation of tetrapyrroles by reactive oxygen species | Synechocystis sp. | |
| isoascorbate | prevents degradation of tetrapyrroles by reactive oxygen species | Chlamydomonas reinhardtii | |
| isoascorbate | prevents degradation of tetrapyrroles by reactive oxygen species | Synechocystis sp. | |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 1,10-phenanthroline | chelation of Fe2+ | Chlamydomonas reinhardtii | |
| 1,10-phenanthroline | chelation of Fe2+ | Synechocystis sp. | |
| 2,2'-bipyridyl | chelation of Fe2+ | Chlamydomonas reinhardtii | |
| 4-chloromercuribenzene sulfonate | partial inhibition of intact chloroplasts at 2.5 mM | Chlamydomonas reinhardtii | |
| EDTA | chelation of Fe3+ | Chlamydomonas reinhardtii | |
| FeSO4 | - |
Chlamydomonas reinhardtii | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| chloroplast | - |
Chlamydomonas reinhardtii | 9507 | - |
| membrane | - |
Chlamydomonas reinhardtii | 16020 | - |
| membrane | - |
Synechocystis sp. | 16020 | - |
| soluble | - |
Synechocystis sp. | - |
- |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Fe2+ | requirement | Chlamydomonas reinhardtii | |
| Fe2+ | requirement | Synechocystis sp. | |
| FeSO4 | when added with 1,10-phenanthroline | Synechocystis sp. | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + O2 | Chlamydomonas reinhardtii | - |
131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + H2O | - |
? | |
| 131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + O2 | Synechocystis sp. | - |
131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + H2O | - |
? | |
| 131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + H+ + O2 | Chlamydomonas reinhardtii | - |
divinylprotochlorophyllide + NADP+ + 2 H2O | - |
? | |
| 131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + H+ + O2 | Synechocystis sp. | - |
divinylprotochlorophyllide + NADP+ + 2 H2O | - |
? | |
| magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + H+ + O2 | Chlamydomonas reinhardtii | - |
131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + H2O | - |
? | |
| magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + H+ + O2 | Synechocystis sp. | - |
131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + H2O | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Chlamydomonas reinhardtii | - |
- |
- |
| Synechocystis sp. | - |
PCC6803 | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| partial | Synechocystis sp. |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + O2 | - |
Chlamydomonas reinhardtii | 131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + H2O | - |
? | |
| 131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + O2 | - |
Synechocystis sp. | 131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + H2O | - |
? | |
| 131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + H+ + O2 | - |
Chlamydomonas reinhardtii | divinylprotochlorophyllide + NADP+ + 2 H2O | - |
? | |
| 131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + H+ + O2 | - |
Synechocystis sp. | divinylprotochlorophyllide + NADP+ + 2 H2O | - |
? | |
| magnesium-mesoporphyrin IX + NADPH + O2 | - |
Synechocystis sp. | diethyl protochlorophyllide + NADP+ + H2O | - |
? | |
| magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + H+ + O2 | - |
Chlamydomonas reinhardtii | 131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + H2O | - |
? | |
| magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + H+ + O2 | - |
Synechocystis sp. | 131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + H2O | - |
? | |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 30 | - |
assay at | Chlamydomonas reinhardtii |
| 30 | - |
assay at | Synechocystis sp. |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NADPH | requirement | Chlamydomonas reinhardtii | |
| NADPH | requirement | Synechocystis sp. | |
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Release 2023.1 (January 2023)
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