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Literature summary for 1.14.13.8 extracted from
- Characteristic properties and kinetic analysis with neurotoxins of porcine FAD-containing monooxygenase (1994), Biochim. Biophys. Acta, 1208, 204-210.
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.018 | - |
N,N-Dimethylaniline | - |
Sus scrofa |  |
| 0.028 | - |
NADPH | with dimethylaniline | Sus scrofa | |
| 0.038 | - |
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine | - |
Sus scrofa | |
| 0.043 | - |
O2 | with dimethylaniline | Sus scrofa | |
| 0.049 | - |
O2 | with dimethylaniline | Sus scrofa | |
| 0.05 | - |
NADPH | with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine | Sus scrofa | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| microsome | - |
Sus scrofa | - |
- |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 56000 | - |
SDS-PAGE, gel filtration | Sus scrofa |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Sus scrofa | - |
- |
- |
Posttranslational Modification
| Posttranslational Modification | Comment | Organism |
|---|---|---|
| glycoprotein | amino acid analysis | Sus scrofa |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| amino acid composition | Sus scrofa |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Sus scrofa | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 1,2,3,4-tetrahydroisoquinoline + NADPH + O2 | - |
Sus scrofa | ? | - |
? | |
| 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine + NADPH + O2 | - |
Sus scrofa | ? | - |
? | |
| 1-methyl-6,7-dihydroxytetrahydroisoquinoline + NADPH + O2 | - |
Sus scrofa | ? | - |
? | |
| N,N-dimethylaniline + NADPH + H+ + O2 | - |
Sus scrofa | N,N-dimethylaniline N-oxide + NADP+ + H2O | - |
r | |
| N,N-dimethylaniline + NADPH + O2 | - |
Sus scrofa | N,N-dimethylaniline N-oxide + NADP+ + H2O | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| monomer | 1 * 56000, gel filtration | Sus scrofa |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 25 | - |
- |
Sus scrofa |
| 32 | - |
- |
Sus scrofa |
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