Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | there is decreased eNOS activity in tight-skin 1-mouse skin tissue | Mus musculus | |
N(G)-nitroarginine methyl ester | - |
Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | P70313 | tight-skin 1 mouse strain | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
blood plasma | - |
Mus musculus | - |
endothelial cell | - |
Mus musculus | - |
hair follicle | - |
Mus musculus | - |
lung | - |
Mus musculus | - |
skin | n the skin, eNOS is present in the epidermal layer, hair follicles and also in the endothelial cells lining the blood vessels | Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2 L-arginine + 3 NADPH + 3 H+ + 4 O2 | - |
Mus musculus | 2 citrulline + 2 nitric oxide + 3 NADP+ + 4 H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
endothelial nitric oxide synthase | - |
Mus musculus |
eNOS | - |
Mus musculus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
5,6,7,8-tetrahydro-L-biopterin | - |
Mus musculus | |
Calmodulin | - |
Mus musculus | |
NADPH | - |
Mus musculus |
Organism | Comment | Expression |
---|---|---|
Mus musculus | expression of both the eNOS protein and gene is significantly reduced in tight-skin 1-mouse skin tissue | up |