Protein Variants | Comment | Organism |
---|---|---|
additional information | generation of mice chimeric for iNOS expression, wild-type animals receive bone marrow cells from CD45.1-expressing congenic wild-type mice, resulting in three different chimeric strains, phenotype with induced colitis, overview | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
2 L-arginine + 3 NADPH + 3 H+ + 4 O2 | Mus musculus | - |
2 citrulline + 2 nitric oxide + 3 NADP+ + 4 H2O | - |
? | |
additional information | Mus musculus | inducible nitric-oxide synthase-derived NO contributes to the pathophysiology of intestinal inflammation in the colon | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
C57BL/6 wild-type mice | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
blood | iNOS | Mus musculus | - |
colon | iNOS | Mus musculus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
iNOS activities in wild-type and chimeric mice, both with induced colitis, overview | Mus musculus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2 L-arginine + 3 NADPH + 3 H+ + 4 O2 | - |
Mus musculus | 2 citrulline + 2 nitric oxide + 3 NADP+ + 4 H2O | - |
? | |
additional information | inducible nitric-oxide synthase-derived NO contributes to the pathophysiology of intestinal inflammation in the colon | Mus musculus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
inducible nitric-oxide synthase | - |
Mus musculus |
iNOS | - |
Mus musculus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | - |
Mus musculus |