Activating Compound | Comment | Organism | Structure |
---|---|---|---|
alpha-naphthoflavone | 60% activiation at 25 mM | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
- |
Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
4-nitrophenol | mutual competitive inhibition with chlorzoxazone | Homo sapiens | |
alpha-naphthoflavone | slight | Homo sapiens | |
chlorzoxazone | mutual competitive inhibition with 4-nitrophenol | Homo sapiens | |
coumarin | slight | Homo sapiens | |
diethyldithiocarbamate | 50% inhibition at 0.002-0.003 mM | Homo sapiens | |
mephenytoin | slight | Homo sapiens | |
quinidine | slight | Homo sapiens | |
sulfaphenazole | slight | Homo sapiens | |
troleandomycin | slight | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.021 | - |
4-nitrocatechol | cDNA expressed enzyme | Homo sapiens | |
0.03 | - |
4-nitrocatechol | - |
Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Homo sapiens | - |
- |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
40000 | - |
SDS-PAGE | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
human | - |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-nitrophenol + NADH + O2 | - |
Homo sapiens | 4-nitrocatechol + NAD+ + H2O | - |
? | |
chlorzoxazone + NADH + O2 | 6-hydroxylation | Homo sapiens | ? | - |
? |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.042 | - |
4-nitrophenol | inhibition of chlorzoxazone 6-hydroxylation | Homo sapiens | |
0.047 | - |
chlorzoxazone | inhibition of 4-nitrophenol hydroxylation | Homo sapiens |