Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Zn2+ | 1 mM, complete inhibition | Mus musculus | |
Zn2+ | 1 mM, complete inhibition | Rattus norvegicus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Fe2+ | absence of the cofactor Fe2+ does not completely abolish enzyme activity, even when endogenous Fe2+ is removed from the homogenate with a gel filtration column | Mus musculus | |
Fe2+ | absence of the cofactor Fe2+ does not completely abolish enzyme activity, even when endogenous Fe2+ is removed from the homogenate with a gel filtration column | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
heart | - |
Mus musculus | - |
heart | - |
Rattus norvegicus | - |
kidney | - |
Mus musculus | - |
kidney | - |
Rattus norvegicus | - |
liver | - |
Mus musculus | - |
liver | - |
Rattus norvegicus | - |
testis | - |
Mus musculus | - |
testis | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
N6,N6,N6-trimethyl-L-lysine + 2-oxoglutarate + O2 | - |
Mus musculus | 3-hydroxy-N6,N6,N6-trimethyl-L-lysine + succinate + CO2 | - |
? | |
N6,N6,N6-trimethyl-L-lysine + 2-oxoglutarate + O2 | - |
Rattus norvegicus | 3-hydroxy-N6,N6,N6-trimethyl-L-lysine + succinate + CO2 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
6-N-trimethyllysine dioxygenase | - |
Mus musculus |
6-N-trimethyllysine dioxygenase | - |
Rattus norvegicus |
TML dioxygenase | - |
Mus musculus |
TML dioxygenase | - |
Rattus norvegicus |
TMLD | - |
Mus musculus |
TMLD | - |
Rattus norvegicus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ascorbate | 10 mM | Mus musculus | |
ascorbate | 10 mM | Rattus norvegicus |