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Literature summary for 1.14.11.38 extracted from

  • Kato, N.; Suzuki, H.; Takagi, H.; Uramoto, M.; Takahashi, S.; Osada, H.
    Gene disruption and biochemical characterization of verruculogen synthase of Aspergillus fumigatus (2011), ChemBioChem, 12, 711-714.
    View publication on PubMed
Search for more literature for 1.14.11.38

Activating Compound

Activating Compound Comment Organism Structure
ascorbate not essential but involved in the FtmF reaction Aspergillus fumigatus

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli as a His6-tagged fusion protein Aspergillus fumigatus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.003
-
 2-oxoglutarate pH 6.0, 30°C Aspergillus fumigatus
0.021
-
 fumitremorgin B pH 6.0, 30°C Aspergillus fumigatus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
77000
-
 gel filtration Aspergillus fumigatus

Organism

Organism UniProt Comment Textmining
Aspergillus fumigatus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Aspergillus fumigatus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
fumitremorgin B + 2-oxoglutarate + 2 O2 + AH2
-
 Aspergillus fumigatus verruculogen + succinate + CO2 + H2O + A
-
 ?

Synonyms

Synonyms Comment Organism
FtmF
-
 Aspergillus fumigatus

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
37
-
 10 min, 10% loss of activity Aspergillus fumigatus

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
0.19
-
 fumitremorgin B pH 6.0, 30°C Aspergillus fumigatus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6
-
-
 Aspergillus fumigatus