Literature summary for 1.14.11.26 extracted from

Wu, X.B.; Fan, K.Q.; Wang, Q.H.; Yang, K.Q.
C-terminus mutations of Acremonium chrysogenum deacetoxy/deacetylcephalosporin C synthase with improved activity toward penicillin analogs (2005), FEMS Microbiol. Lett., 246, 103-110.

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Protein Variants

Protein Variants	Comment	Organism
N305L	improved ability to convert penicillin analogs in ring expansion reaction of EC 1.14.20.1	Acremonium chrysogenum
R308L	improved ability to convert penicillin analogs in ring expansion reaction of EC 1.14.20.1	Acremonium chrysogenum

Organism

Organism	UniProt	Comment	Textmining
Acremonium chrysogenum	-	catalyzes both reaction of EC 1.14.20.1 and of EC 1.14.11.26	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
7-aminodeacetoxycephalosporanic acid + 2-oxoglutarate + O2	poor substrate	Acremonium chrysogenum	7-aminodeacetylcephalosporin + succinate + CO2	-	?

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Release 2023.1 (January 2023)