Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|
Synonyms | Comment | Organism |
---|---|---|
PHD1 | - |
Mus musculus |
PHD2 | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
malfunction | PHD1-/- mice have statistically non-significant reductions in infarct volumes following middle cerebral artery occlusion compared with their littermates at this time-point in this model | Mus musculus |
malfunction | PHD2+/- mice have significantly increased microvessel density, improved cerebral blood flow on reperfusion, and show significantly better functional outcomes and higher locomotor activity associated with significantly fewer apoptotic cells in the penumbra and significantly less blood-brain-barrier disruption with a trend to reduced infarct volumes 24 h after the middle cerebral artery occlusion than littermate controls | Mus musculus |