Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
27900 | - |
x * 27900, calculated | Xenopus laevis |
45300 | - |
x * 45300, calculated | Xenopus laevis |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Xenopus laevis | Q6DFD1 | isoform PHD45 | - |
Xenopus laevis | Q6DFD1 | isoforms PHD28 | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
embryo | in embryonic development, isoform PHD45 expression is complementary to that of PHD28. Hypoxia-inducible factor HIF-1alpha protein level is maximal around stage 20 when expression of PHD45 disappears, while expression of PHD28 reaches a maximum at stage 20. Overexpression of the ubiquitin ligase Seven-in-Absentia homolog Siah2 decreases PHD45, but not PHD28, and causes the small-eye phenotype of Xenopus | Xenopus laevis | - |
Subunits | Comment | Organism |
---|---|---|
? | x * 27900, calculated | Xenopus laevis |
? | x * 45300, calculated | Xenopus laevis |
More | protein contains MYND-type zinc finger and oxygenase domains | Xenopus laevis |