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Literature summary for 1.14.11.2 extracted from

  • Nissi, R.; Bohling, T.; Autio-Harmainen, H.
    Immunofluorescence localization of prolyl 4-hydroxylase isoenzymes and type I and II collagens in bone tumours: type I enzyme predominates in osteosarcomas and chondrosarcomas, whereas type II enzyme predominates in their benign counterparts (2004), Acta Histochem., 106, 111-121.
    View publication on PubMed
Search for more literature for 1.14.11.2

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
procollagen L-proline + 2-oxoglutarate + O2 Homo sapiens
-
 procollagen trans-4-hydroxy-L-proline + succinate + CO2
-
 ?
procollagen L-proline + 2-oxoglutarate + O2 Rattus norvegicus
-
 procollagen trans-4-hydroxy-L-proline + succinate + CO2
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
chondroblastoma cell
-
 Homo sapiens
-
chondrocyte
-
 Homo sapiens
-
chondrosarcoma cell predominantly type I prolyl-4-hydroxylase Homo sapiens
-
osteochondroma cell
-
 Homo sapiens
-
osteosarcoma cell ATCC ROS 17/2.8, strong expression of type I alpha subunit Rattus norvegicus
-
osteosarcoma cell predominantly type I prolyl-4-hydroxylase Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
procollagen L-proline + 2-oxoglutarate + O2
-
 Homo sapiens procollagen trans-4-hydroxy-L-proline + succinate + CO2
-
 ?
procollagen L-proline + 2-oxoglutarate + O2
-
 Rattus norvegicus procollagen trans-4-hydroxy-L-proline + succinate + CO2
-
 ?

Synonyms

Synonyms Comment Organism
type I proly 4-hydroxylase
-
 Rattus norvegicus
type I proyl 4-hydroxylase
-
 Homo sapiens
type II proyl 4-hydroxylase
-
 Homo sapiens