Activating Compound | Comment | Organism | Structure |
---|---|---|---|
SCP-2 | phytanoylis efficiently 2-hydroxylated by PAHX in vitro in the presence of mature SCO-2. SCP-2 increases discrimination between straight-chain and branched-chain substrates, i.e. it decreases activity with straight chain substrates and increase activity with branched-chain substrates. In vivo substrates for PAHX may be SCP-2 complexes | Homo sapiens |
Application | Comment | Organism |
---|---|---|
diagnostics | the substrate phytanoyl-CoA is difficult to handle because of its amphipathic properties. Commercially available alternative substrates, such as hexadecanoyl-CoA or isovaleryl-CoA are potentially usefull | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
butanoyl-CoA + 2-oxoglutarate + O2 | - |
Homo sapiens | 2-hydroxybutanoyl-CoA + succinate + CO2 | - |
? | |
decanoyl-CoA + 2-oxoglutarate + O2 | - |
Homo sapiens | 2-hydroxydecanoyl-CoA + succinate + CO2 | - |
? | |
dodecanoyl-CoA + 2-oxoglutarate + O2 | - |
Homo sapiens | 2-hydroxydodecanoyl-CoA + succinate + CO2 | - |
? | |
hexadecanoyl-CoA + 2-oxoglutarate + O2 | - |
Homo sapiens | 2-hydroxyhexadecanoyl-CoA + succinate + CO2 | - |
? | |
hexanoyl-CoA + 2-oxoglutarate + O2 | - |
Homo sapiens | 2-hydroxyhexanoyl-CoA + succinate + CO2 | - |
? | |
isovaleryl-CoA + 2-oxoglutarate + O2 | - |
Homo sapiens | ? | - |
? | |
octadecanoyl-CoA + 2-oxoglutarate + O2 | - |
Homo sapiens | 2-hydroxyoctadecanoyl-CoA + succinate + CO2 | - |
? | |
octanoyl-CoA + 2-oxoglutarate + O2 | - |
Homo sapiens | 2-hydroxyoctanoyl-CoA + succinate + CO2 | - |
? | |
phytanoyl-CoA + 2-oxoglutarate + O2 | - |
Homo sapiens | 2-hydroxyphytanoyl-CoA + succinate + CO2 | - |
? | |
tetradecanoyl-CoA + 2-oxoglutarate + O2 | - |
Homo sapiens | 2-hydroxytetradecanoyl-CoA + succinate + CO2 | - |
? |