Cloned (Comment) | Organism |
---|---|
in bacterial expression vector pQE-31 | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2-methylhexadecanoyl-CoA | 56% of control activity | Homo sapiens | |
hexadecanoyl-CoA | 74% of control activity | Homo sapiens |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Fe2+ | requirement | Homo sapiens | |
Fe2+ | requirement | Rattus norvegicus | |
Mg2+ | - |
Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
human | - |
Rattus norvegicus | - |
rat | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Homo sapiens | - |
liver | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
3-methylhexadecanoyl-CoA + 2-oxoglutarate + O2 | - |
Homo sapiens | 2-hydroxy-3-methylhexadecanoyl-CoA + succinate + CO2 | - |
? | |
3-methylhexadecanoyl-CoA + 2-oxoglutarate + O2 | - |
Rattus norvegicus | 2-hydroxy-3-methylhexadecanoyl-CoA + succinate + CO2 | - |
? | |
phytanoyl-CoA + 2-oxoglutarate + O2 | - |
Rattus norvegicus | alpha-hydroxyphytanoyl-CoA + succinate + CO2 | - |
? | |
phytanoyl-CoA + 2-oxoglutarate + O2 | no activity with octadecanoyl-CoA, lignoceroyl-CoA, 2-methylhexadecanoyl-CoA and 4,8,12-trimethyltridecanoyl-CoA | Homo sapiens | alpha-hydroxyphytanoyl-CoA + succinate + CO2 | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Homo sapiens | |
ATP | - |
Rattus norvegicus | |
GTP | - |
Homo sapiens | |
additional information | UTP, CTP, ITP, AMP, ADP, NAD+ and FAD can not act as cofactors, ATP and GTP can be replaced by adenosine-5'-O-(3-thiotriphosphate), adenylylimidodiphosphate, adenylyl-(beta,gamma-methylene)-diphosphonate and guanylyl-imidodiphosphate | Homo sapiens |