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Literature summary for 1.14.11.1 extracted from

  • Ziering, D.L.; Pascal, R.A.
    Mechanism-based inhibition of bacterial gamma-butyrobetaine hydroxylase (1990), J. Am. Chem. Soc., 112, 834-838.
No PubMed abstract available
Search for more literature for 1.14.11.1

Inhibitors

Inhibitors Comment Organism Structure
3-(2,2-Dimethylcyclopropyl)propionic acid mechanism-based inhibitor Pseudomonas sp.

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.4
-
 gamma-butyrobetaine
-
 Pseudomonas sp.

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
 Pseudomonas sp. 5737
-

Organism

Organism UniProt Comment Textmining
Pseudomonas sp.
-
 AK1
-
Pseudomonas sp. AK1
-
 AK1
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-trimethylammoniobutanoate + 2-oxoglutarate + O2
-
 Pseudomonas sp. 3-hydroxy-4-trimethylammoniobutanoate + succinate + CO2
-
 ?
4-trimethylammoniobutanoate + 2-oxoglutarate + O2
-
 Pseudomonas sp. AK1 3-hydroxy-4-trimethylammoniobutanoate + succinate + CO2
-
 ?
5,5-dimethylhexanoate + 2-oxoglutarate + O2 poor substrate, 20% of the decarboxylation events lead to hydroxylation Pseudomonas sp. ?
-
 ?
5,5-dimethylhexanoate + 2-oxoglutarate + O2 poor substrate, 20% of the decarboxylation events lead to hydroxylation Pseudomonas sp. AK1 ?
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Pseudomonas sp.