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Literature summary for 1.13.12.5 extracted from

  • Santos, E.B.; Yeh, R.; Lee, J.; Nikhamin, Y.; Punzalan, B.; Punzalan, B.; La Perle, K.; Larson, S.M.; Sadelain, M.; Brentjens, R.J.
    Sensitive in vivo imaging of T cells using a membrane-bound Gaussia princeps luciferase (2009), Nat. Med., 15, 338-344.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.13.12.5

Activating Compound

Activating Compound Comment Organism Structure
additional information membrane-anchored GLuc leads to an 9fold increased bioluminescent signal in fibroblasts compared to GLuc Gaussia princeps

Application

Application Comment Organism
additional information imaging of T cells in the context of a competent immune system, bioluminescent imaging Gaussia princeps

Cloned(Commentary)

Cloned (Comment) Organism
expression in mouse and human C57/BL6 primary T cells, expression in PG-13 cells Renilla sp.
expression in mouse and human C57/BL6 primary T cells, expression in PG-13 cells Gaussia princeps

Protein Variants

Protein Variants Comment Organism
extFLuc membrane-anchored Renilla sp.
extGLuc membrane-anchored Gaussia princeps

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Renilla sp. 5829
-
cytosol
-
 Gaussia princeps 5829
-
membrane membrane-anchored Renilla sp. 16020
-
membrane membrane-anchored Gaussia princeps 16020
-

Organism

Organism UniProt Comment Textmining
Gaussia princeps
-
-
-
Renilla sp.
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
coelenterazine + O2
-
 Renilla sp. ?
-
 ?
coelenterazine + O2
-
 Gaussia princeps ?
-
 ?
D-luciferin + O2
-
 Renilla sp. ?
-
 ?
D-luciferin + O2
-
 Gaussia princeps ?
-
 ?

Synonyms

Synonyms Comment Organism
extGLuc
-
 Gaussia princeps
extRLuc
-
 Renilla sp.
Gaussia luciferase enzyme
-
 Gaussia princeps
membrane-anchored RLUc
-
 Renilla sp.
Renilla luciferase
-
 Renilla sp.
RLuc
-
 Renilla sp.