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Literature summary for 1.13.12.5 extracted from

  • Hanson, J.; Reese, J.; Gorman, J.; Cash, J.; Fraizer, G.
    Hormone treatment enhances WT1 activation of renilla luciferase constructs in LNCaP cells (2007), Front. Biosci., 12, 1387-1394.
    View publication on PubMed

Application

Application Comment Organism
analysis the use of control Renilla luciferase vectors as normalizers requires that they not be influenced by any variables in the experiment. The zinc finger transcription factor WT1 effect on luciferase activation varies from no significant effect in 293 and PC3 cells to strong enhancement in LNCaP cells treated with the androgen analog R1881. Hormone enhances WT1-mediated activation of luciferase and these interactions require an intact WT1 zinc finger DNA binding domain Renilla reniformis

Cloned(Commentary)

Cloned (Comment) Organism
expression in LNCaP cell, pRL-SV40 cell, pRL-null cell Renilla reniformis

Organism

Organism UniProt Comment Textmining
Renilla reniformis
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