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Literature summary for 1.13.12.2 extracted from

  • Yamauchi, T.; Yamamoto, S.; Hayaishi, O.
    A possible involvement of sulfhydryl groups in the conversion of lysine monooxygenase to an oxidase (1975), J. Biol. Chem., 250, 7127-7133.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
p-chloromercuribenzoate increases oxidase and dehydrogenase activities, maximal rate of oxidation of lysine at 4-5 mol p-chloromercuribenzoate per mol enzyme, for arginine at 3 mol per mol enzyme Pseudomonas fluorescens

Inhibitors

Inhibitors Comment Organism Structure
additional information alkylating and oxidizing reagents convert oxygenase to oxidase; various sulfhydryl reagents including certain mercurials Pseudomonas fluorescens
p-chloromercuribenzoate conversion of oxygenase to oxidase; increases oxidase and dehydrogenase activities, decreases oxygenase activity Pseudomonas fluorescens

Organism

Organism UniProt Comment Textmining
Pseudomonas fluorescens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-arginine + O2 monooxygenase activity Pseudomonas fluorescens 4-guanidinobutyramide + CO2 + H2O
-
?
L-arginine + O2 oxidase activity Pseudomonas fluorescens 2-amino-5-guanidinovalerate + NH3 + H2O2
-
?
L-lysine + O2 monooxygenase activity Pseudomonas fluorescens 5-aminopentanamide + CO2 + H2O
-
?
L-lysine + O2 oxidase activity Pseudomonas fluorescens 2-keto-6-amino-n-hexanoate + NH3 + H2O2
-
?