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Literature summary for 1.13.11.8 extracted from
- Water and nitric oxide binding by protocatechuate 4,5-dioxygenase and catechol 2,3-dioxygenase. Evidence for binding of exogenous ligands to the active site Fe2+ of extradiol dioxygenases (1985), J. Biol. Chem., 260, 14035-14044.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 3-Amino-4-hydroxybenzoic acid | - |
Comamonas testosteroni |  |
| 3-Chloro-4-hydroxybenzoic acid | - |
Comamonas testosteroni | |
| 3-Fluoro-4-hydroxybenzoic acid | - |
Comamonas testosteroni | |
| 3-Hydroxy-4-aminobenzoic acid | - |
Comamonas testosteroni | |
| 3-hydroxybenzoate | - |
Comamonas testosteroni | |
| 3-Iodo-4-hydroxybenzoic acid | - |
Comamonas testosteroni | |
| 3-methoxy-4-hydroxybenzoic acid | - |
Comamonas testosteroni | |
| 3-Nitro-4-hydroxybenzoic acid | - |
Comamonas testosteroni | |
| 4-hydroxybenzoate | - |
Comamonas testosteroni | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.08 | - |
protocatechuate | - |
Comamonas testosteroni | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| protocatechuate + O2 | Comamonas testosteroni | - |
4-carboxy-2-hydroxymuconate semialdehyde | - |
? | |
| protocatechuate + O2 | Comamonas testosteroni Pt-L5 / ATCC 49249 | - |
4-carboxy-2-hydroxymuconate semialdehyde | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Comamonas testosteroni | - |
- |
- |
| Comamonas testosteroni | - |
grown on 4-hydroxybenzoate containing medium | - |
| Comamonas testosteroni Pt-L5 / ATCC 49249 | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 3,4-dihydroxyphenyl sulfonate + O2 | - |
Comamonas testosteroni | 2-hydroxy-6-oxo-4-sulfohexa-2,4-dienoate | - |
? | |
| 3,4-dihydroxyphenyl sulfonate + O2 | - |
Comamonas testosteroni Pt-L5 / ATCC 49249 | 2-hydroxy-6-oxo-4-sulfohexa-2,4-dienoate | - |
? | |
| protocatechuate + O2 | - |
Comamonas testosteroni | 4-carboxy-2-hydroxymuconate semialdehyde | - |
? | |
| protocatechuate + O2 | - |
Comamonas testosteroni Pt-L5 / ATCC 49249 | 4-carboxy-2-hydroxymuconate semialdehyde | - |
? | |
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