Literature summary for 1.13.11.67 extracted from

Prado-Cabrero, A.; Estrada, A.F.; Al-Babill, S.; Avalos, J.
Identification and biochemical characterization of a novel carotenoid oxygenase: elucidation of the cleavage step in the Fusarium carotenoid pathway (2007), Mol. Microbiol., 64, 448-460.

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Cloned(Commentary)

Cloned (Comment)	Organism
expression in Escherichia coli	Fusarium fujikuroi

Protein Variants

Protein Variants	Comment	Organism
G71D	mutant accumulates torulene instead of the final product of the pathway, neurosporaxanthin	Fusarium fujikuroi

Organism

Organism	UniProt	Comment	Textmining
Fusarium fujikuroi	A1KQY3	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
beta-apo-10'-carotenal + O2	-	Fusarium fujikuroi	retinal + ?	-	?
beta-apo-8'-carotenal + O2	-	Fusarium fujikuroi	(2E,4E,6E,8E,10E)-5,9-dimethyl-11-(2,6,6-trimethylcyclohex-1-en-1-yl)undeca-2,4,6,8,10-pentaenal + (2E,4E)-2-methylhepta-2,4-dienedial	-	?
beta-apo-8'-lycopenal + O2	-	Fusarium fujikuroi	crocetindial + ?	main product	?
lycopene + O2	-	Fusarium fujikuroi	?	eccentric cleavage close to the end of lycopene	?
additional information	enzyme cleaves at the third double bond from the uncycled tail of carotenoids with preference for non-oxygenated tails	Fusarium fujikuroi	?	-	?
torulene + O2	-	Fusarium fujikuroi	beta-apo-4'-carotenal + 3-methylbut-2-enal	-	?

Synonyms

Synonyms	Comment	Organism
CarT	-	Fusarium fujikuroi
torulene oxygenase	-	Fusarium fujikuroi

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Release 2023.1 (January 2023)