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Literature summary for 1.13.11.63 extracted from

  • Grolier, P.; Duszka, C.; Borel, P.; Alexandre-Gouabau, M.C.; Azais-Braesco, V.
    In vitro and in vivo inhibition of beta-carotene dioxygenase activity by canthaxanthin in rat intestine (1997), Arch. Biochem. Biophys., 348, 233-238.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
canthaxanthin mixed inhibition Rattus norvegicus
zeaxanthin non-competitive Rattus norvegicus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0035
-
13-cis-beta-carotene
-
Rattus norvegicus
0.0057
-
all-trans-beta-carotene
-
Rattus norvegicus
0.0062
-
alpha-carotene
-
Rattus norvegicus
0.0067
-
beta-cryptoxanthin
-
Rattus norvegicus
0.0077
-
beta-apo-8'-carotenal
-
Rattus norvegicus
0.0085
-
beta-apo-8'-carotenal
-
Rattus norvegicus
0.0092
-
beta-apo-10'-carotenal
-
Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
intestine
-
Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
13-cis-beta-carotene + O2 11.4% of the activity with all-trans-beta-carotene Rattus norvegicus retinal
-
?
alpha-carotene + O2 8.2% of the activity with all-trans-beta-carotene Rattus norvegicus retinal
-
?
beta-apo-10'-carotenal + O2
-
Rattus norvegicus ?
-
r
beta-apo-8'-carotenal + O2
-
Rattus norvegicus ?
-
r
beta-cryptoxanthin + O2
-
Rattus norvegicus ?
-
r

Synonyms

Synonyms Comment Organism
betaCDIOX
-
Rattus norvegicus

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.0016
-
canthaxanthin
-
Rattus norvegicus
0.0078
-
zeaxanthin
-
Rattus norvegicus