Literature summary for 1.13.11.59 extracted from

Saelices, L.; Youssar, L.; Holdermann, I.; Al-Babili, S.; Avalos, J.
Identification of the gene responsible for torulene cleavage in the Neurospora carotenoid pathway (2007), Mol. Genet. Genomics, 278, 527-537.

Search for more literature for 1.13.11.59

Cloned(Commentary)

Cloned (Comment)	Organism
expression as GST fusion protein	Neurospora crassa

Organism

Organism	UniProt	Comment	Textmining
Neurospora crassa	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	no substrate: beta-carotene	Neurospora crassa	?	-	?
torulene + O2	-	Neurospora crassa	beta-apo-4'-carotenal + 3-methylbut-2-enal	reaction is almost quantitative	?

Synonyms

Synonyms	Comment	Organism
Cao-2	-	Neurospora crassa

Expression

Organism	Comment	Expression
Neurospora crassa	Cao-2 exhibits the same transcriptional pattern as Al-2, which encodes the phytoene synthase/beta-cyclase. The mRNA levels for both genes are very low in vegetative mycelia grown in the dark, and increase markedly upon illumination. Illumination does not lead to any detectable increase of the Cao-2 and Al-2 mRNA amounts in wc-1 or wc-2 mutants, confirming that Cao-2 photoinduction is mediated by the WC-1/WC-2 photoreceptor system	additional information

General Information

General Information	Comment	Organism
physiological function	disruption of cao-2 leads to changes in the carotenoid content, as indicated by the reddish color of several transformants. Mutants accumulate a high proportion of neutral carotenoids including a high content of torulene	Neurospora crassa

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Release 2023.1 (January 2023)