Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
linoleate + O2 | Arabidopsis thaliana | - |
(9S,10E,12Z)-9-hydroperoxy-10,12-octadecadienoate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Arabidopsis thaliana | - |
gene lox1 | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
linoleate + O2 | - |
Arabidopsis thaliana | (9S,10E,12Z)-9-hydroperoxy-10,12-octadecadienoate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
9-lipoxygenase | - |
Arabidopsis thaliana |
9-LOX | - |
Arabidopsis thaliana |
General Information | Comment | Organism |
---|---|---|
malfunction | partial impairment of lox1 and dox1, encoding 9-lipoxygenase and alpha-dioxygenase, mutants to activate systemic acquired resistance against virulent Pseudomonas syringae pv. tomato strain Pst DC3000, enhanced susceptibility of lox1 to the virulent Pseudomonas syringae pv. tomato strain Pst DC3000. 9-Ketooctadecatrienoic acid levels are reduced in lox1 and lox1 dox1 plants but strongly increased in the dox1 mutant due to metabolic interaction of the two pathways. Mutant lox1 dox1 seedlings are hypersensitive to the growth-inhibitory effect of abscisic acid and show enhanced activation of abscisic acid-inducible marker genes as compared with wild-type plants. Phenotypes, overview | Arabidopsis thaliana |
metabolism | plant 9-lipoxygenases and alpha-dioxygenases initiate the synthesis of oxylipins after bacterial infection. Pretreatment with 9-LOX- and alpha-DOX-generated oxylipins protected plant tissues against bacterial infection, especially 9-oxo-10(E),12(Z),15(Z)-octadecatrienoic acid, which is produced from linolenic acid by 9-LOX | Arabidopsis thaliana |
physiological function | the LOX1 pathway is involved in regulating abscisic acid responses | Arabidopsis thaliana |