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Literature summary for 1.13.11.52 extracted from

  • Samikkannu, T.; Rao, K.V.; Gandhi, N.; Saxena, S.K.; Nair, M.P.
    Human immunodeficiency virus type 1 clade B and C Tat differentially induce indoleamine 2,3-dioxygenase and serotonin in immature dendritic cells: Implications for neuroAIDS (2010), J. NeuroVirol., 16, 255-263.
    View publication on PubMed
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Localization

Localization Comment Organism GeneOntology No. Textmining

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-tryptophan + O2 Homo sapiens
-
 N-formyl-L-kynurenine
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
dendritic cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-tryptophan + O2
-
 Homo sapiens N-formyl-L-kynurenine
-
 ?

Synonyms

Synonyms Comment Organism
IDO
-
 Homo sapiens

Expression

Organism Comment Expression
Homo sapiens treatment with 25 ng HIV-1 clade B Tat protein significantly upregulates IDO gene and protein expression 24 h after incubation compared to HIV-1 clade C Tat protein up