Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
endothelial cell | arterially derived, express little indoleamine 2,3-dioxygenase, which is poorly upregulated upon activation (except by mycoplasma) | Homo sapiens | - |
HSVEC cell | i.e. human umbilical vein endothelial cell, express little indoleamine 2,3-dioxygenase, which is poorly upregulated upon activation (except by mycoplasma) | Homo sapiens | - |
HUVEC cell | in HUVEC cells the enzyme is upregulated by incubation with cytokines or in mycoplasma-infected cells. Inhibition of indoleamine 2,3-dioxygenase improves ability of HUVEC cells to stimulate T-cell proliferation | Homo sapiens | - |