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Literature summary for 1.13.11.52 extracted from

  • Beutelspacher, S.C.; Tan, P.H.; McClure, M.O.; Larkin, D.F.; Lechler, R.I.; George, A.J.
    Expression of indoleamine 2,3-dioxygenase (IDO) by endothelial cells: implications for the control of alloresponses (2006), Am. J. Transplant., 6, 1320-1330.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Homo sapiens
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Source Tissue

Source Tissue Comment Organism Textmining
endothelial cell arterially derived, express little indoleamine 2,3-dioxygenase, which is poorly upregulated upon activation (except by mycoplasma) Homo sapiens
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HSVEC cell i.e. human umbilical vein endothelial cell, express little indoleamine 2,3-dioxygenase, which is poorly upregulated upon activation (except by mycoplasma) Homo sapiens
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HUVEC cell in HUVEC cells the enzyme is upregulated by incubation with cytokines or in mycoplasma-infected cells. Inhibition of indoleamine 2,3-dioxygenase improves ability of HUVEC cells to stimulate T-cell proliferation Homo sapiens
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