Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2,2'-dipyridyl | 5 mM, complete inhibition | Drosophyllum lusitanicum |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
homogentisate + O2 | Phaseolus vulgaris | homogentisate ring-cleavage pathway, key enzyme of the ring-cleavage reaction in the catabolic sequence of enzymes from L-tyrosine to acetoacetate and fumarate | 4-maleylacetoacetate | - |
? | |
homogentisate + O2 | Glycine max | homogentisate ring-cleavage pathway, key enzyme of the ring-cleavage reaction in the catabolic sequence of enzymes from L-tyrosine to acetoacetate and fumarate | 4-maleylacetoacetate | - |
? | |
homogentisate + O2 | Daucus carota | homogentisate ring-cleavage pathway, key enzyme of the ring-cleavage reaction in the catabolic sequence of enzymes from L-tyrosine to acetoacetate and fumarate | 4-maleylacetoacetate | - |
? | |
homogentisate + O2 | Nicotiana sylvestris | homogentisate ring-cleavage pathway, key enzyme of the ring-cleavage reaction in the catabolic sequence of enzymes from L-tyrosine to acetoacetate and fumarate | 4-maleylacetoacetate | - |
? | |
homogentisate + O2 | Ruta graveolens | homogentisate ring-cleavage pathway, key enzyme of the ring-cleavage reaction in the catabolic sequence of enzymes from L-tyrosine to acetoacetate and fumarate | 4-maleylacetoacetate | - |
? | |
homogentisate + O2 | Melilotus albus | homogentisate ring-cleavage pathway, key enzyme of the ring-cleavage reaction in the catabolic sequence of enzymes from L-tyrosine to acetoacetate and fumarate | 4-maleylacetoacetate | - |
? | |
homogentisate + O2 | Coleus scutellarioides | homogentisate ring-cleavage pathway, key enzyme of the ring-cleavage reaction in the catabolic sequence of enzymes from L-tyrosine to acetoacetate and fumarate | 4-maleylacetoacetate | - |
? | |
homogentisate + O2 | Agrostemma githago | homogentisate ring-cleavage pathway, key enzyme of the ring-cleavage reaction in the catabolic sequence of enzymes from L-tyrosine to acetoacetate and fumarate | 4-maleylacetoacetate | - |
? | |
homogentisate + O2 | Agave toumeyana | homogentisate ring-cleavage pathway, key enzyme of the ring-cleavage reaction in the catabolic sequence of enzymes from L-tyrosine to acetoacetate and fumarate | 4-maleylacetoacetate | - |
? | |
homogentisate + O2 | Drosophyllum lusitanicum | homogentisate ring-cleavage pathway, key enzyme of the ring-cleavage reaction in the catabolic sequence of enzymes from L-tyrosine to acetoacetate and fumarate | 4-maleylacetoacetate | - |
? | |
homogentisate + O2 | Pimpinella anisum | homogentisate ring-cleavage pathway, key enzyme of the ring-cleavage reaction in the catabolic sequence of enzymes from L-tyrosine to acetoacetate and fumarate | 4-maleylacetoacetate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Agave toumeyana | - |
- |
- |
Agrostemma githago | - |
- |
- |
Coleus scutellarioides | - |
- |
- |
Daucus carota | - |
- |
- |
Drosophyllum lusitanicum | - |
- |
- |
Glycine max | - |
- |
- |
Melilotus albus | - |
- |
- |
Nicotiana sylvestris | - |
- |
- |
Phaseolus vulgaris | - |
var. nanus | - |
Pimpinella anisum | - |
- |
- |
Ruta graveolens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
190fold purification | Drosophyllum lusitanicum |
partial purification | Phaseolus vulgaris |
partial purification | Glycine max |
partial purification | Daucus carota |
partial purification | Nicotiana sylvestris |
partial purification | Ruta graveolens |
partial purification | Melilotus albus |
partial purification | Coleus scutellarioides |
partial purification | Agrostemma githago |
partial purification | Agave toumeyana |
partial purification | Pimpinella anisum |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
- |
Drosophyllum lusitanicum |
0.125 | - |
- |
Melilotus albus |
0.17 | - |
- |
Pimpinella anisum |
0.25 | - |
- |
Daucus carota |
0.39 | - |
- |
Ruta graveolens |
0.405 | - |
- |
Agrostemma githago |
0.495 | - |
- |
Glycine max |
0.515 | - |
- |
Phaseolus vulgaris |
0.625 | - |
- |
Agave toumeyana |
1.16 | - |
- |
Nicotiana sylvestris |
2.59 | - |
- |
Coleus scutellarioides |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
homogentisate + O2 | - |
Phaseolus vulgaris | 4-maleylacetoacetate | - |
? | |
homogentisate + O2 | - |
Glycine max | 4-maleylacetoacetate | - |
? | |
homogentisate + O2 | - |
Daucus carota | 4-maleylacetoacetate | - |
? | |
homogentisate + O2 | - |
Nicotiana sylvestris | 4-maleylacetoacetate | - |
? | |
homogentisate + O2 | - |
Ruta graveolens | 4-maleylacetoacetate | - |
? | |
homogentisate + O2 | - |
Melilotus albus | 4-maleylacetoacetate | - |
? | |
homogentisate + O2 | - |
Coleus scutellarioides | 4-maleylacetoacetate | - |
? | |
homogentisate + O2 | - |
Agrostemma githago | 4-maleylacetoacetate | - |
? | |
homogentisate + O2 | - |
Agave toumeyana | 4-maleylacetoacetate | - |
? | |
homogentisate + O2 | - |
Drosophyllum lusitanicum | 4-maleylacetoacetate | - |
? | |
homogentisate + O2 | - |
Pimpinella anisum | 4-maleylacetoacetate | - |
? | |
homogentisate + O2 | homogentisate ring-cleavage pathway, key enzyme of the ring-cleavage reaction in the catabolic sequence of enzymes from L-tyrosine to acetoacetate and fumarate | Phaseolus vulgaris | 4-maleylacetoacetate | - |
? | |
homogentisate + O2 | homogentisate ring-cleavage pathway, key enzyme of the ring-cleavage reaction in the catabolic sequence of enzymes from L-tyrosine to acetoacetate and fumarate | Glycine max | 4-maleylacetoacetate | - |
? | |
homogentisate + O2 | homogentisate ring-cleavage pathway, key enzyme of the ring-cleavage reaction in the catabolic sequence of enzymes from L-tyrosine to acetoacetate and fumarate | Daucus carota | 4-maleylacetoacetate | - |
? | |
homogentisate + O2 | homogentisate ring-cleavage pathway, key enzyme of the ring-cleavage reaction in the catabolic sequence of enzymes from L-tyrosine to acetoacetate and fumarate | Nicotiana sylvestris | 4-maleylacetoacetate | - |
? | |
homogentisate + O2 | homogentisate ring-cleavage pathway, key enzyme of the ring-cleavage reaction in the catabolic sequence of enzymes from L-tyrosine to acetoacetate and fumarate | Ruta graveolens | 4-maleylacetoacetate | - |
? | |
homogentisate + O2 | homogentisate ring-cleavage pathway, key enzyme of the ring-cleavage reaction in the catabolic sequence of enzymes from L-tyrosine to acetoacetate and fumarate | Melilotus albus | 4-maleylacetoacetate | - |
? | |
homogentisate + O2 | homogentisate ring-cleavage pathway, key enzyme of the ring-cleavage reaction in the catabolic sequence of enzymes from L-tyrosine to acetoacetate and fumarate | Coleus scutellarioides | 4-maleylacetoacetate | - |
? | |
homogentisate + O2 | homogentisate ring-cleavage pathway, key enzyme of the ring-cleavage reaction in the catabolic sequence of enzymes from L-tyrosine to acetoacetate and fumarate | Agrostemma githago | 4-maleylacetoacetate | - |
? | |
homogentisate + O2 | homogentisate ring-cleavage pathway, key enzyme of the ring-cleavage reaction in the catabolic sequence of enzymes from L-tyrosine to acetoacetate and fumarate | Agave toumeyana | 4-maleylacetoacetate | - |
? | |
homogentisate + O2 | homogentisate ring-cleavage pathway, key enzyme of the ring-cleavage reaction in the catabolic sequence of enzymes from L-tyrosine to acetoacetate and fumarate | Drosophyllum lusitanicum | 4-maleylacetoacetate | - |
? | |
homogentisate + O2 | homogentisate ring-cleavage pathway, key enzyme of the ring-cleavage reaction in the catabolic sequence of enzymes from L-tyrosine to acetoacetate and fumarate | Pimpinella anisum | 4-maleylacetoacetate | - |
? |