Literature summary for 1.13.11.4 extracted from

Chua, C.H.; Feng, Y.; Yeo, C.C.; Khoo, H.E.; Poh, C.L.
Identification of amino acid residues essential for catalytic activity of gentisate 1,2-dioxygenase from Pseudomonas alcaligenes NCIB 9867 (2001), FEMS Microbiol. Lett., 204, 141-146.

Search for more literature for 1.13.11.4

Cloned(Commentary)

Cloned (Comment)	Organism
-	Pseudomonas alcaligenes

Protein Variants

Protein Variants	Comment	Organism
H108D	no enzymatic activity	Pseudomonas alcaligenes
H110D	no enzymatic activity	Pseudomonas alcaligenes
H149D	no enzymatic activity	Pseudomonas alcaligenes
H151D	no enzymatic activity	Pseudomonas alcaligenes
additional information	double mutant Phe3Leu, Val334Ala, doubled enzymatic activity, mutants in conserved core regions with less activity	Pseudomonas alcaligenes

Organism

Organism	UniProt	Comment	Textmining
Pseudomonas alcaligenes	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2,5-dihydroxybenzoate + O2	-	Pseudomonas alcaligenes	maleylpyruvate	-	?

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Release 2023.1 (January 2023)