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Literature summary for 1.13.11.34 extracted from

  • Mahshid, Y.; Lisy, M.; Wang, X.; Spanbroek, R.; Flygare, J.; Christensson, B.; Bjoerkholm, M.; Sander, B.; Habenicht, A.; Claesson, H.
    High expression of 5-lipoxygenase in normal and malignant mantle zone B lymphocytes (2009), BMC Immunol., 10, 2-2.
    View publication on PubMedView publication on EuropePMC

Localization

Localization Comment Organism GeneOntology No. Textmining
nucleus tonsillar polymorphonuclear granulocytes Homo sapiens 5634
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Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
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Source Tissue

Source Tissue Comment Organism Textmining
additional information Granta 519 cell and JEKO-1 cell Homo sapiens
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REC-1 cell
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Homo sapiens
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tonsil high expression of 5-lipoxygenase in mantle zone B cells from tonsils, weak expression in germinal centre cells and no expression in plasma cells from tonsils. High expression in mantle B cell lymphoma and weak or no expression in follicular lymphoma. Primary leukemized mantle B cell lymphoma (B-prolymphocytic leukaemia cells) and mantle B cell lymphoma cell lines also expressed 5-lipoxygenase Homo sapiens
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Synonyms

Synonyms Comment Organism
5-lipoxygenase
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Homo sapiens
5-LO
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Homo sapiens

General Information

General Information Comment Organism
physiological function role of the 5-lipoxygenase pathway in B cells before the cells finally differentiate to plasma cells Homo sapiens