Literature summary for 1.13.11.34 extracted from

Poeckel, D.; Niedermeyer, T.H.; Pham, H.T.; Mikolasch, A.; Mundt, S.; Lindequist, U.; Lalk, M.; Werz, O.
Inhibition of human 5-lipoxygenase and anti-neoplastic effects by 2-amino-1,4-benzoquinones (2006), Med. Chem., 2, 591-595.

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Inhibitors

Inhibitors	Comment	Organism	Structure
2-[4'-(iso-propylphenyl)-amino]-5,6-dimethyl-1,4-benzoquinone	potent inhibitor, IC50: 0.006 mM	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
leukocyte	-	Homo sapiens	-

IC50 Value

IC50 Value	IC50 Value Maximum	Comment	Organism	Inhibitor	Structure
0.006	-	potent inhibitor, IC50: 0.006 mM	Homo sapiens	2-[4'-(iso-propylphenyl)-amino]-5,6-dimethyl-1,4-benzoquinone

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Release 2023.1 (January 2023)