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Literature summary for 1.13.11.31 extracted from

  • Hamasaki, Y.; Tai, H.H.
    Gossypol, a potent inhibitor of arachidonate 5- and 12-lipoxygenases (1985), Biochim. Biophys. Acta, 834, 37-41.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
5-Hydroxydopamine
-
Rattus norvegicus
6-Hydroxydopamine
-
Rattus norvegicus
chlorpromazine
-
Rattus norvegicus
eicosatetraynoic acid
-
Rattus norvegicus
esculetin
-
Rattus norvegicus
fluphenazine
-
Rattus norvegicus
gossypol acetic acid non-competitive with respect to arachidonate Rattus norvegicus
Trifluoperazine
-
Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
leukemia cell basophilic Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
arachidonate + O2 i.e. 5Z,8Z,11Z,14Z-eicosatetraenoic acid Rattus norvegicus (5Z,8Z,10E,14Z)-(12S)-12-hydroperoxyicosa-5,8,10,14-tetraenoate
-
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