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Literature summary for 1.13.11.27 extracted from

  • Lindstedt, S.; Rundgren, M.
    Inhibition of 4-hydroxyphenylpyruvate dioxygenase from Pseudomonas sp. strain P.J. 874 the enol tautomer of the substrate (1982), Biochim. Biophys. Acta, 704, 66-74.
    View publication on PubMed
Search for more literature for 1.13.11.27

Inhibitors

Inhibitors Comment Organism Structure
1,2-dihydroxybenzene-3,5-disulfonic acid inhibition is prevented by ascorbate but not reversed by enol-4-hydroxyphenylpyruvate Pseudomonas sp.
4-hydroxyphenylpyruvate interaction of enol-4-hydroxyphenylpyruvate with enzyme-bound Fe3+, formed by autooxidation, causes the substrate inhibition Pseudomonas sp.

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
additional information
-
 additional information
-
 Pseudomonas sp.

Organism

Organism UniProt Comment Textmining
Pseudomonas sp.
-
-
-
Pseudomonas sp. P.J. 874
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-hydroxyphenylpyruvate + O2
-
 Pseudomonas sp. homogentisate + CO2
-
 ?
4-hydroxyphenylpyruvate + O2
-
 Pseudomonas sp. P.J. 874 homogentisate + CO2
-
 ?

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
37
-
 pH 7.5, 0.64 M Tris-HCl, stable for 7.5 min Pseudomonas sp.

pH Stability

pH Stability pH Stability Maximum Comment Organism
7.5
-
 37°C, 7.5 min, stable Pseudomonas sp.

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
additional information
-
 additional information
-
 Pseudomonas sp.