KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | kinetics of enzyme-substrate complexes of the active site of MII-containing quercetin 2,3-dioxygenase, overview | Aspergillus japonicus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Cu2+ | required, mononuclear copper(II) active site, binding structure, X-ray diffraction and NMR analysis, overview. Direct coordinative interaction between copper(II) ion and the carboxylate group of Glu73. Complexes modeling, overview | Aspergillus japonicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
quercetin + O2 | Aspergillus japonicus | - |
2-(3,4-dihydroxybenzoyloxy)-4,6-dihydroxybenzoate + CO + H+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Aspergillus japonicus | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
glycoprotein | - |
Aspergillus japonicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | quercetin 2,3-dioxygenase activates molecular oxygen to catalyze the oxygenative ring-opening reaction of the O-heterocycle of quercetin to the corresponding depside (phenolic carboxylic acid esters) and carbon monoxide | Aspergillus japonicus | ? | - |
? | |
quercetin + O2 | - |
Aspergillus japonicus | 2-(3,4-dihydroxybenzoyloxy)-4,6-dihydroxybenzoate + CO + H+ | - |
? |
Subunits | Comment | Organism |
---|---|---|
homodimer | bicupin enzyme | Aspergillus japonicus |
Synonyms | Comment | Organism |
---|---|---|
2,3-QD | - |
Aspergillus japonicus |
General Information | Comment | Organism |
---|---|---|
additional information | synthesis of a series of flavonolate complexes as structural and functional models for the enzyme-substrate complexes of the active site of MII-containing quercetin 2,3-dioxygenase, structure analysis, overview | Aspergillus japonicus |