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Literature summary for 1.13.11.20 extracted from

  • Oien, D.B.; Moskovitz, J.
    Ablation of the mammalian methionine sulfoxide reductase A affects the expression level of cysteine dioxygenase (2007), Biochem. Biophys. Res. Commun., 352, 556-559.
    View publication on PubMed
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Application

Application Comment Organism
medicine lack of methionine sulfoxide reductase MsrA in liver of MsrA -/- mice leads to a significant drop in the cellular level of thiol groups and lowers the level of cysteine dioxygenase expression. Following selenium deficient diet applied to decrease the expression levels of selenoproteins like MsrB, the latter effect is maintained while the basal levels of thiol decreased in both wild-type strains and strains deficient for methionine dioxygenase Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Mus musculus cysteine dioxygenase and methionine sulfoxide reductase are working in coordination to balance cellular antioxidant level ?
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 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
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 strain lacking methionine sulfoxide reductase MsrA
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Source Tissue

Source Tissue Comment Organism Textmining
liver lack of methionine sulfoxide reductase MsrA in liver of MsrA -/- mice leads to a significant drop in the cellular level of thiol groups and lowers the level of cysteine dioxygenase expression. Following selenium deficient diet applied to decrease the expression levels of selenoproteins like MsrB, the latter effect is maintained while the basal levels of thiol decreased in both wild-type strains and strains deficient for methionine dioxygenase Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information cysteine dioxygenase and methionine sulfoxide reductase are working in coordination to balance cellular antioxidant level Mus musculus ?
-
 ?