Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | P0ACD8 | large subunit HyaB | - |
Escherichia coli | P69739 | small subunit HyaA | - |
Synonyms | Comment | Organism |
---|---|---|
HyaA | - |
Escherichia coli |
HyaB | - |
Escherichia coli |
HYD1 | - |
Escherichia coli |
General Information | Comment | Organism |
---|---|---|
physiological function | growth of a strain that lacks a functional fructose phosphotransferase system in the presence of fructose results in an approximately 10fold increase in isoform Hyd1 levels in comparison with growth under the same conditions with glucose. This increase in the amount of Hyd1 is not due to regulation at the transcriptional level. Reintroduction of a functional fructose phosphotransferase system restores growth on D-fructose and reduces Hyd1 levels to those observed after growth on D-glucose. Reducing the rate of glucose uptake by introducing a mutation in the gene encoding the cAMP receptor protein, or consumption through glycolysis, by introducing a mutation in phosphoglucose isomerase, increased Hyd1 levels during growth on glucose. Thus the ability to oxidize hydrogen by Hyd1 shows a strong correlation with the rate of carbon flow through glycolysis and provides a direct link between hydrogen, carbon and energy metabolism | Escherichia coli |