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Literature summary for 1.12.99.6 extracted from
- Theoretical study of dioxygen induced inhibition of [FeFe]-hydrogenase (2009), Inorg. Chem., 48, 7127-7140.
Application
| Application | Comment | Organism |
|---|---|---|
| industry | inhibition by dioxygen is a major drawback for the application of [FeFe]-hydrogenase in hydrogen fuel production or as electrocatalysts for hydrogen oxidation in fuel cells | Clostridium pasteurianum |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| O2 | the direct interaction of the [2Fe]H subsite with dioxygen is an exothermic and specific reaction in which O2 most favorably binds in an end-on manner to the distal iron. Irreversibility of dioxygen-induced enzyme inactivation by water release and degradation of the ligand environment of the H-cluster | Clostridium pasteurianum |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Clostridium pasteurianum | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| H2 + oxidized electron acceptor | - |
Clostridium pasteurianum | H+ + reduced electron acceptor | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| [FeFe]-hydrogenase | - |
Clostridium pasteurianum |
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