Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Mus musculus | 5829 | - |
mitochondrion | - |
Mus musculus | 5739 | - |
nucleus | - |
Mus musculus | 5634 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
selenium | selenoprotein | Mus musculus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
19000 | - |
isozyme c-GPx4, SDS-PAGE | Mus musculus |
34000 | - |
isozyme n-GPx4, SDS-PAGE | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | Q5XJZ8 | fragment | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
astrocyte | - |
Mus musculus | - |
hippocampus | - |
Mus musculus | - |
neuron | - |
Mus musculus | - |
spermatocyte | isozyme n-GPx-4 is specifically expressed in late spermatocytes | Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
glutathione + ROOH | - |
Mus musculus | glutathione disulfide + ROH + H2O | - |
? | |
H2O2 + GSH | - |
Mus musculus | H2O + GSSG | - |
? | |
additional information | does not accept thioredoxin as hydrogen donor | Mus musculus | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
monomer | 1 * 19000, isozyme c-GPx4, SDS-PAGE | Mus musculus |
monomer | 1 * 34000, isozyme c-GPx4, SDS-PAGE | Mus musculus |
Synonyms | Comment | Organism |
---|---|---|
c-GPx4 | isoform, cytosolic GPx4 | Mus musculus |
glutathione peroxidase 4 | - |
Mus musculus |
GPx4 | - |
Mus musculus |
m-GPx4 | isoform, mitochondrial GPx4 | Mus musculus |
n-GPx4 | isoform, nuclear GPx4 | Mus musculus |
PHGPX | - |
Mus musculus |
phospholipid hydroperoxide glutathione peroxidase | - |
Mus musculus |