Activating Compound | Comment | Organism | Structure |
---|---|---|---|
etoposide | activates p53, wich induces the expression of glutathione peroxidase | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
glutathione + ROOH | Homo sapiens | - |
glutathione disulfide + ROH + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
Saos-2 cell line | - |
Homo sapiens | - |
U2-OS cell line | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
5 | - |
Saos-2 | Homo sapiens |
5.5 | - |
Saos-2 treated with etoposide | Homo sapiens |
6.7 | - |
U2-OS | Homo sapiens |
11.9 | - |
U2-OS treated with etoposide | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
glutathione + ROOH | - |
Homo sapiens | glutathione disulfide + ROH + H2O | - |
? |