Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | increased activity of catalase in tumor cells recombinantly overexpressing IGFBP-2 probably mediated through IGF-independent mechanisms | Mus musculus | |
additional information | increased activity of catalase in tumor cells recombinantly overexpressing IGFBP-2 probably mediated through IGF-independent mechanisms | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
293 cell | epithelial cell | Homo sapiens | - |
adrenocortical carcinoma cell | Y-1 cell, increased activity of catalase in tumor cells recombinantly overexpressing IGFBP-2 probably mediated through IGF-independent mechanisms | Mus musculus | - |
Caco-2 cell | adrenocortical tumor cell, increased activity of catalase in tumor cells recombinantly overexpressing IGFBP-2 probably mediated through IGF-independent mechanisms | Mus musculus | - |
Caco-2 cell | colon tumor cell, increased activity of catalase in tumor cells recombinantly overexpressing IGFBP-2 probably mediated through IGF-independent mechanisms | Homo sapiens | - |
colonic cancer cell | Caco-2 cell, increased activity of catalase in tumor cells recombinantly overexpressing IGFBP-2 probably mediated through IGF-independent mechanisms | Homo sapiens | - |
epithelial cell | 293 cell | Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
1.5 | - |
about, cell lysates of wild-type Caco-2 cells | Homo sapiens |
3.5 | 4.5 | about, cell lysates of wild-type Y-1 cells | Mus musculus |
6 | - |
about, cell lysates of Caco-2 cells recombinantly overexpressing IGFBP-2 | Homo sapiens |
8 | - |
about, cell lysates of Y-1 cells recombinantly overexpressing IGFBP-2 | Mus musculus |
77.5 | - |
about, cell lysates of wild-type and recombinantly IGFBP-2-overexpressing 293 cells | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
H2O2 | - |
Mus musculus | O2 + H2O | - |
? | |
H2O2 | - |
Homo sapiens | O2 + H2O | - |
? |